Structural biology can provide a coherent picture of medically relevant phenomena, such as regulation of homeostasis and pathogenesis. Our laboratory has been focusing on the determination of structures of membrane proteins associated with human diseases by X-ray crystallography. An increasing emphasis has been placed on computational approaches to rational design and screening of novel pharmacologically active compounds as well as molecular dynamics simulation.
Our goals include developing a comprehensive understanding of life at the atomic and molecular levels and applying this knowledge to elucidate basic principles of modulation of cellular functions with therapeutic benefits.
Kyoto 606-8501, Japan
* Please replace [at] with @.